Akadx (Acalabrutinib) 100mg*60 | BigBear Laos Generic | GLT

Generic Information: Akadx (Acalabrutinib) 100mg — Laos

Akadx is a Lao-manufactured generic of acalabrutinib produced by BigBear Pharmaceutical Co., Ltd., a Vientiane-based manufacturer with a growing oncology portfolio. The product is supplied as 100 mg capsules in 60-capsule packs, the standard strength for the twice-daily acalabrutinib regimen. Akadx is BigBear's acalabrutinib brand for mantle cell lymphoma, chronic lymphocytic leukemia and small lymphocytic lymphoma.

BigBear uses a "-dx" suffix across its oncology line, so buyers familiar with other BigBear products will recognise Akadx as its acalabrutinib offering. As a second-generation BTK inhibitor, acalabrutinib was engineered for greater selectivity than the first-in-class agent, and its 100 mg twice-daily dosing is well established for B-cell malignancies.

What Is Akadx Used For?

Akadx treats mantle cell lymphoma (MCL) in patients with at least one prior therapy, and chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). It delivers the same covalent BTK inhibition as the originator, controlling the malignant B-cell population that drives these diseases.

How Does Akadx Work?

The active ingredient, acalabrutinib, covalently and irreversibly inhibits Bruton's tyrosine kinase (BTK) by binding to a cysteine in its active site. Since BTK transmits survival and growth signals from the B-cell receptor, its blockade starves the malignant B cells of the signals they need, slowing disease progression in MCL, CLL and SLL.

Indications

• Mantle cell lymphoma (MCL) after at least one prior therapy.
• Chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL).

Dosage and Administration

Take 100 mg twice daily, about every 12 hours, swallowing the capsule whole with water and with or without food. Do not chew, crush or open the capsules. If a dose is missed by more than 3 hours, skip it and resume at the next scheduled time. Regular blood counts are advised.

Side Effects

The most common adverse reactions are infections, low blood counts (neutropenia, anaemia, thrombocytopenia), headache, dizziness, diarrhoea, nausea, rash, fatigue and musculoskeletal pain. Serious risks include bleeding, serious infections, second primary cancers, atrial fibrillation and liver injury. Report unusual bleeding, palpitations or infection signs promptly.

Storage

Store Akadx below 30°C in the original packaging, away from moisture and out of children's reach. Do not use past the expiry date.

Why Choose the GLT?

GLT verifies each Akadx batch against BigBear's manufacturing records and offers a documented, traceable supply route for Lao generics. Lao-produced acalabrutinib is priced at a small fraction of the originator's US list price, making long-term twice-daily therapy far more affordable for patients and institutions. We provide purchase documentation and direct contact for support.

How to Order Akadx from GLT

To order Akadx 100 mg (60 capsules), reach GLT on WhatsApp at +86 15234153837 or email [email protected]. Share your quantity, destination and order type, and we confirm batch details and lead time before dispatching.

FAQ

Is Akadx the same as Calquence? Akadx contains the same active ingredient (acalabrutinib) at 100 mg; it is a generic by BigBear Pharmaceutical in Laos.

How is it dosed? 100 mg twice daily, approximately every 12 hours, with or without food.

Can GLT ship Akadx internationally? Yes — contact us on WhatsApp or email for availability.