Trepmac (Brigatinib) 90mg*30's/60's | Generic ALK Inhibitor Bangladesh | GLT

Generic Information: Trepmac (Bangladesh)

Trepmac is a Bangladeshi generic of brigatinib, manufactured by Genvio Pharmaceuticals (Bangladesh) Limited. It is supplied as 90 mg tablets in 30-tablet and 60-tablet packs. The 60-tablet pack is a convenient two-month supply at the standard maintenance dose, reducing the frequency of re-ordering for patients on long-term therapy.

What Is Trepmac Used For?

Trepmac is used to treat anaplastic lymphoma kinase-positive (ALK+) non-small cell lung cancer, including in patients whose disease has progressed on or who cannot tolerate crizotinib. As an oral, once-daily medicine, it is well suited to continuous home treatment, and it is prescribed only after a genetic test confirms the ALK rearrangement.

How Does Trepmac (Brigatinib) Work?

Brigatinib, the active ingredient in Trepmac, is a next-generation ALK tyrosine kinase inhibitor that also inhibits ROS1, IGF-1R, and FLT-3. It blocks the growth signals that sustain ALK-positive cancer cells and penetrates the brain, helping control brain metastases. The generic Trepmac carries the same mechanism and active ingredient as the originator at a lower price.

Indications

Trepmac is indicated for adults with ALK-positive, locally advanced or metastatic NSCLC. It is not appropriate for ALK-negative disease and is not indicated for small-cell lung cancer. Confirm the ALK mutation status with an approved test before starting therapy.

Dosage

The recommended regimen is 90 mg once daily for 7 days, then 180 mg once daily if tolerated. The 90 mg tablets in this listing are used for the lead-in phase and as a reduced maintenance dose where needed. Take the tablet with or without food and swallow it whole. Do not make up for a missed dose by taking an extra tablet.

Side Effects

Common adverse reactions include diarrhea, rash, cough, high blood pressure, fatigue, nausea, muscle pain, and headache. Regular blood pressure monitoring is advised, and diarrhea is usually manageable with supportive care. Interstitial lung disease is rare but serious and requires permanent discontinuation if confirmed.

Storage

Store Trepmac below 30°C in a dry place, in its original container, and out of the reach of children. No refrigeration is needed.

Why Choose the GLT?

For patients who pay for treatment themselves, a Bangladeshi generic like Trepmac offers a substantial cost saving over the originator brand, whose Western list price is very high. GLT sources from established manufacturers and provides the documentation required for safe international shipping, helping patients maintain affordable, uninterrupted therapy.

How to Order

To order Trepmac through GLT, contact us on WhatsApp at +86 15234153837 or email [email protected]. Provide the pack size and destination country, and we will confirm availability, sourcing origin, and delivery terms. We support both institutional purchasers and individual patients.

FAQ

Is Trepmac a generic of Alunbrig? Yes. Trepmac is a Bangladeshi generic of brigatinib, the active ingredient in Alunbrig, manufactured by Genvio Pharmaceuticals.

What pack sizes does Trepmac come in? Trepmac is available in 90 mg tablets in 30-tablet and 60-tablet packs. The larger pack is convenient for long-term maintenance dosing.

Can I buy generic brigatinib online? Generic brigatinib can be purchased through international suppliers such as GLT. Always confirm the supplier's legitimacy and request proper documentation before ordering.