LuciMito (Mitotane) 500mg 100 Tablets | Lucius Laos Generic | GLT

Generic Information: LuciMito (Mitotane) — Lucius Laos Generic

LuciMito is the mitotane product of Lucius Pharmaceuticals (Lao) Co., Ltd., the Vientiane manufacturer whose 25,000-square-meter plant produces more than two hundred medicines across oncology and rare-disease fields. The product carries Lao registration number 12 L 14XX/26 and comes as 500 mg × 100 tablets per box, matching the originator's standard strength and pack size. Lucius names its products with the Luci- prefix across its portfolio, and LuciMito follows that convention for its mitotane.

What Is LuciMito (Mitotane) Used For?

LuciMito is indicated for adult patients with unresectable, metastatic or recurrent adrenocortical carcinoma, and it is also used to control the excessive corticosteroid secretion and related clinical symptoms that hormone-producing ACC causes — the Cushing's syndrome picture that makes functional tumors so dangerous. For patients who cannot reach or sustain the originator, a Lao generic registered with the Ministry of Health is the realistic path to continuous treatment of this ultra-rare cancer.

How Does LuciMito (Mitotane) Work?

The active ingredient mitotane is a specific adrenal cytotoxic agent that selectively destroys the cells of the adrenal cortex's zona fasciculata and zona reticularis while suppressing corticosteroid synthesis and release, and it also blocks the conversion of cholesterol to corticosteroids. The combined effect lowers the abnormal cortisol, androgen and other hormone levels that functional tumors produce, shrinks lesions over time, and relieves the metabolic complications of hormone excess. As with all mitotane, the molecule is lipophilic and clears slowly, so therapy is steered by blood-level monitoring.

Indications of LuciMito (Laos)

The Lao indication covers adult patients with unresectable, metastatic or recurrent adrenocortical carcinoma, plus the control of excessive corticosteroid secretion and its symptoms from hormone-producing ACC. This aligns with the global label's core — inoperable functional or nonfunctional ACC — and with mitotane's established off-label use in Cushing's syndrome. The product is for adults; pediatric use has not been established.

Dosage and Administration

The recommended starting dose is 2 g per day (four 500 mg tablets), divided into three or four oral doses, taken with food to improve absorption. The dose is then escalated stepwise according to blood levels and tolerance, up to a maximum maintenance dose not exceeding 10 g per day, targeting a plasma mitotane level of 14–20 mg/L. Tablets are swallowed whole — never chewed or crushed. If a dose is missed it may be taken if more than 12 hours remain before the next one; otherwise skip it and never double up. Once disease is stable, the dose is maintained at the lowest effective level for long-term therapy.

Side Effects of LuciMito

The common reactions (≥20%) are nausea, vomiting, diarrhea, anorexia, fatigue, drowsiness, dizziness and rash, with laboratory abnormalities including elevated transaminases, dyslipidemia, abnormal thyroid function and adrenal insufficiency. The serious risks are the class-defining ones: adrenal crisis during shock, trauma or infection (the boxed warning, requiring temporary discontinuation and exogenous steroids), central nervous system toxicity rising sharply above 20 mg/L, hepatotoxicity and fetal harm. Effective nonhormonal contraception is required during treatment, and breastfeeding is not recommended.

Storage Instructions

Store in a dry place at 20–25°C, with short excursions allowed between 15°C and 30°C, sealed and protected from light. Keep out of children's reach. Unused tablets — a cytotoxic medicine — should be returned to a pharmacy for disposal, not thrown in household waste.

Why Choose LuciMito from GLT?

LuciMito's value is a documented Lao registration plus Lucius' established rare-disease manufacturing track record, delivered at a price point that keeps long-term ACC therapy affordable — typically far below the originator for the same 500 mg strength. GLT adds the verification that generics buying depends on: sealed boxes, the registration number 12 L 14XX/26 on the packaging, batch documentation and pre-shipment photographs of the exact stock, plus a direct human line on WhatsApp +86 15234153837 or [email protected]. We quote LuciMito against MITODX, Mytanne and the Lysodren originals so your choice rests on facts.

How to Order LuciMito (Mitotane)

Contact GLT on WhatsApp +86 15234153837 or at [email protected] with your quantity. You receive a formal quotation with courier and payment options — usually within one working day — and sealed stock is dispatched with export documentation on confirmation. Continuous monthly supply can be scheduled so therapy is never interrupted.

FAQ

What is LuciMito's registration number? Lao registration 12 L 14XX/26, issued by the Lao Ministry of Health and printed on the packaging.

Who makes LuciMito? Lucius Pharmaceuticals (Lao) Co., Ltd., the Vientiane manufacturer known for its Luci- branded oncology and rare-disease portfolio.

What dose do patients start on? 2 g per day (four tablets) in divided doses with food, then escalated against blood levels toward the 14–20 mg/L target, up to a maximum of 10 g per day.

Does LuciMito help with Cushing's symptoms? Yes — by suppressing corticosteroid synthesis it controls the hormone-excess symptoms that functional ACC tumors cause.

Is it the same as Lysodren? Same active ingredient (mitotane 500 mg) and same purpose; LuciMito is Lucius' Lao-registered generic with its own packaging and documentation.