Pemidx (Pemigatinib) 4.5mg*14 | BigBear Laos Generic | GLT

Generic Information: Pemidx (Pemigatinib) 4.5mg — Laos

Pemidx is a Lao-manufactured generic of pemigatinib, produced by BigBear Pharmaceutical Co., Ltd., a Laos-based manufacturer that builds oncology generics under Lao GMP conditions. The product is supplied as 4.5 mg film-coated tablets in 14-tablet packs, matching the originator's lowest strength. Pemidx is BigBear's pemigatinib brand for FGFR2-altered cholangiocarcinoma, giving patients an alternative supply route without changing the treatment protocol their oncologist has established.

Note that the brand is spelled "Pemidx" — an important detail for buyers verifying a batch, as similar-sounding names appear across regional generics. Because the originator's standard dose is 13.5 mg once daily on a 14-days-on/7-days-off schedule, the 4.5 mg strength is typically used for dose adjustment or titration, so buyers should confirm their physician's prescribed strength before ordering.

What Is Pemidx Used For?

Pemidx is prescribed for adults with previously treated, unresectable locally advanced or metastatic cholangiocarcinoma carrying an FGFR2 fusion or rearrangement. Cholangiocarcinoma is a rare cancer of the bile ducts with few effective options, and pemigatinib is the first targeted therapy developed for the FGFR2-altered subset. Pemidx is used after disease progression on at least one prior line of systemic therapy.

How Does Pemidx Work?

The pemigatinib in Pemidx is a selective inhibitor of FGFR1, FGFR2 and FGFR3 kinases. In tumours with an FGFR2 fusion or rearrangement, the FGFR pathway is constitutively active and drives cell proliferation. Pemidx blocks this signalling, disrupting the growth and survival of cancer cells that depend on FGFR activation.

Indications

• Previously treated, unresectable locally advanced or metastatic cholangiocarcinoma with FGFR2 fusion or rearrangement, confirmed by a validated test.
• Adult patients who have progressed after at least one prior line of systemic therapy.

Dosage and Administration

The recommended pemigatinib dose is 13.5 mg once daily for 14 days, followed by 7 days off, repeated in 21-day cycles. Tablets are swallowed whole with water, with or without food. The 4.5 mg strength of Pemidx supports dose adjustments and is taken as directed by the physician. Monitoring of phosphate, renal function and eye health is advised during treatment.

Side Effects

Common adverse effects include hyperphosphatemia, diarrhoea, stomatitis, dry mouth, fatigue, nausea and alopecia. A notable risk is serous retinal detachment, so patients should report any visual changes promptly and undergo ophthalmologic evaluation. Dry eye, nail changes and liver enzyme elevations may also occur.

Storage

Store Pemidx below 25°C in the original package, in a dry place away from direct light, and out of the reach of children. Do not use after the expiry date.

Why Choose the GLT?

GLT verifies each Pemidx batch against the manufacturer's documentation and provides a transparent, traceable supply route for Lao generics. Lao-made pemigatinib is typically priced at a small fraction of the originator's US list price — often several times lower — making long-term FGFR-targeted therapy far more affordable for patients and institutions. We provide clear purchase documentation and direct, responsive support throughout ordering and delivery.

How to Order Pemidx from GLT

Message GLT on WhatsApp at +86 15234153837 or email [email protected] to order Pemidx 4.5 mg (14 tablets). Tell us your quantity, destination and order type, and we confirm availability, batch details and shipping terms before dispatch.

FAQ

Is Pemidx the same as Pemazyre? Pemidx contains the same active ingredient (pemigatinib) as Pemazyre, manufactured in Laos by BigBear Pharmaceutical.

What is Pemidx used for? It treats cholangiocarcinoma with an FGFR2 fusion or rearrangement in adults who have already received treatment.

Where can I order Pemidx? GLT can supply Pemidx internationally; contact us on WhatsApp or email for availability and shipping.