Ruifeile (Afatinib) 30mg/40mg Tablets | Qilu China Generic | GLT

Generic Information: Ruifeile (Afatinib) — Qilu, China

Ruifeile is a domestic Chinese generic of afatinib produced by Qilu Pharmaceutical Co., Ltd., one of China's largest and most established pharmaceutical manufacturers. Available in 7-tablet strips in both 30 mg and 40 mg strengths, Ruifeile is a nationally consistency-evaluated generic that has also been selected in China's national volume-based procurement program, making it one of the most affordable afatinib options available. Qilu's afatinib received approval and consistency evaluation in 2020, with national drug approval number H20203459.

What Is Ruifeile (Afatinib) Used For?

Ruifeile is used to treat locally advanced or metastatic non-small cell lung cancer with EGFR-activating mutations, including exon 19 deletions, the L858R substitution, and uncommon mutations like G719X, L861Q and S768I. It is a first-line therapy for EGFR-mutant NSCLC and is also used in metastatic squamous NSCLC after progression on platinum-based chemotherapy.

How Does Ruifeile (Afatinib) Work?

Ruifeile contains afatinib, an irreversible pan-ErbB tyrosine kinase inhibitor that covalently binds EGFR, HER2 and ErbB4, permanently blocking the growth signals that EGFR-mutant lung cancer cells rely on. This irreversible mechanism provides durable tumor control and broad activity against uncommon EGFR mutations, distinguishing afatinib from first-generation reversible inhibitors.

Indications

Ruifeile is indicated for adults with locally advanced or metastatic non-small cell lung cancer whose tumors have non-resistant EGFR mutations, and for metastatic squamous NSCLC progressing after platinum-based therapy. EGFR mutation testing is required before treatment.

Dosage

The recommended dose is 40 mg once daily, taken at least one hour before or two hours after a meal. The 7-tablet strip is one week of therapy, and the 30 mg strength supports dose reduction or use in severe renal impairment. Adjustments should be managed by the oncologist.

Side Effects

Common side effects of Ruifeile include diarrhea, acneiform rash, stomatitis, paronychia, dry skin and decreased appetite. Serious reactions such as interstitial lung disease, hepatotoxicity and severe skin disorders are uncommon but require prompt medical attention. Proactive management of diarrhea and skin symptoms is recommended.

Storage

Store Ruifeile in a cool, dry place away from sunlight and moisture, in its original packaging. Keep out of reach of children and swallow tablets whole with water.

Why Choose the GLT?

Ruifeile through GLT offers Qilu's consistency-evaluated afatinib generic at a price that ranks among the most affordable available, thanks to its inclusion in China's national volume-based procurement. As a Hong Kong-licensed supplier, we source genuine stock and provide the documentation needed for confident purchasing. For patients seeking a highly cost-effective, quality-assured afatinib, Ruifeile is a standout option.

How to Order Ruifeile (Afatinib)

Contact us on WhatsApp at +86 15234153837 or by email at [email protected] to order. Share your preferred strength, quantity and destination, and we will confirm availability and delivery.

FAQ

Who makes Ruifeile? Ruifeile is produced by Qilu Pharmaceutical, and its afatinib was approved with consistency evaluation in 2020 under national drug approval number H20203459.

Why is Ruifeile so affordable? Ruifeile is included in China's national volume-based procurement program, which substantially lowers its price while maintaining consistency-evaluated quality.

What strengths are available? Ruifeile is available in 30 mg and 40 mg strengths, both in 7-tablet strips.

Do I need a prescription? Yes, afatinib is a prescription oncology medicine used under physician supervision.