Vizimpro (Dacomitinib) 15mg*30's | China-Sourced EGFR TKI | GLT

Generic Information: Vizimpro (China-Mainland)

This is the China-Mainland version of Vizimpro, the Pfizer brand of dacomitinib. Supplied as 15 mg film-coated tablets in a 30-tablet box, this is the dosing form commonly used in China for dose adjustment or for patients who start on a reduced regimen. Dacomitinib is a second-generation, irreversible EGFR tyrosine kinase inhibitor, and it is taken orally once a day with or without food, a convenience that matters a great deal during long-term cancer care.

What Is Dacomitinib Used For?

Dacomitinib is used as a first-line treatment for locally advanced or metastatic non-small cell lung cancer (NSCLC) with an EGFR exon 19 deletion or exon 21 L858R substitution mutation. In China, the medicine was approved by the National Medical Products Administration (NMPA), and it has been included in the national medical insurance drug list as a Category B (乙类) item, which lowers the out-of-pocket cost for eligible patients.

How Does Dacomitinib Work?

As an irreversible inhibitor of the ErbB family, dacomitinib permanently attaches to EGFR, HER2, and HER4, cutting off the growth signals that drive EGFR-mutated lung cancer. Because the binding is covalent rather than reversible, the anti-tumor effect persists longer than with first-generation drugs such as gefitinib. This is why dacomitinib has demonstrated an overall survival benefit over gefitinib in Asian patients and in the exon 21 L858R subgroup.

Indications

In China, dacomitinib is approved as monotherapy for the first-line treatment of adults with locally advanced or metastatic NSCLC carrying EGFR exon 19 deletion or exon 21 L858R substitution mutations. Genetic testing of tumor tissue or blood is required before prescribing, to confirm the presence of one of these sensitizing mutations.

Dosage

The standard dose is 45 mg once daily. The 15 mg tablets are typically used when the physician reduces the dose to manage adverse reactions, or as part of a step-down schedule. If a dose is missed, skip it and take the next one as scheduled — never take two doses at once. Avoid proton-pump inhibitors; a locally-acting antacid or an H2-receptor antagonist spaced 6 hours before or 10 hours after the dose can be used instead.

Side Effects

Common side effects include diarrhea, rash, paronychia, stomatitis, decreased appetite, dry skin, weight loss, hair loss, cough, and pruritus. Diarrhea is the most frequent event, so early anti-diarrheal treatment and hydration are recommended. Skin reactions are usually managed with moisturizers, sun protection, and, when needed, topical or oral antibiotics. Interstitial lung disease is rare but serious, and treatment must be stopped permanently if it is confirmed.

Storage

Keep the tablets at a temperature not exceeding 30°C, in the original packaging, protected from moisture, and away from children. No refrigeration is required.

Why Choose the China Version of Vizimpro?

The China version of Vizimpro is the same Pfizer molecule, but its reimbursed price is markedly lower than the list price of the same medicine in Western markets. For patients who are eligible for China's national medical insurance, the effective cost can be a fraction of what the same branded drug would cost out-of-pocket in the United States or Europe. This makes the China-sourced version an attractive option for buyers looking for genuine Pfizer dacomitinib at a more affordable price point.

How to Order

To source China-Mainland Vizimpro through GLT, reach us on WhatsApp at +86 15234153837 or email [email protected]. Tell us the strength and pack size you need and your destination country, and we will confirm sourcing origin, current availability, and export documentation. We serve both institutions and individual patients.

FAQ

Is dacomitinib available in China? Yes, dacomitinib is approved in China by the NMPA and is available through the national medical insurance system as a Category B medicine.

Is the China version cheaper than the US version? Generally yes. The reimbursed China price is substantially lower than the US list price, which is why many international buyers consider sourcing from China for genuine Pfizer dacomitinib.

What is the difference between Vizimpro China and Vizimpro US? The active ingredient and dosage are identical; the difference is the packaging, the regulatory market, and, most importantly, the price. Both are genuine Pfizer products.