Osiem (Osimertinib) 80mg*30 | TLPH Laos Generic | GLT
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Generic Information: Osiem (Osimertinib) 80mg — Laos
Osiem is a Lao-manufactured generic of osimertinib, produced by Trans Continental Life Science & Pharmaceuticals (TLPH), a Laos-based pharmaceutical manufacturer. The product is supplied as 80 mg film-coated tablets in 30-tablet bottles, matching the originator's standard strength and pack size. TLPH is among the Lao manufacturers building a portfolio of affordable oncology generics for regional patients who cannot access branded targeted therapies.
The "TLPH" abbreviation appears on packaging and in trade documents, so buyers should recognise both the full company name and the short form when verifying a batch. As with all generics, the active ingredient — osimertinib — is the critical identity marker.
What Is Osiem Used For?
Osiem is used for EGFR mutation-positive non-small cell lung cancer, including first-line therapy for advanced disease, T790M-positive disease after progression on an earlier EGFR TKI, and adjuvant therapy after surgery in eligible EGFR-mutant patients. It is also relevant when brain metastases are present, owing to osimertinib's central nervous system penetration.
How Does Osiem Work?
Osiem's osimertinib irreversibly inhibits mutated EGFR, covering the common sensitising mutations (exon 19 deletion, L858R) and the T790M resistance mutation while sparing wild-type EGFR. This dual, mutant-selective activity is what allows it to work across multiple lines of therapy with a relatively tolerable side-effect profile.
Indications
- First-line advanced EGFR-mutant NSCLC.
- Adjuvant therapy after resection of EGFR-mutant NSCLC.
- T790M-positive NSCLC after prior EGFR-TKI therapy.
Dosage and Administration
Take one 80 mg tablet once daily with or without food, swallowed whole. Do not crush or split. Missed doses beyond 12 hours are omitted. Dose reduction to 40 mg daily may be used for adverse-event management, and treatment continues until progression or intolerance.
Side Effects
Common reactions include diarrhoea, rash, dry skin, nail toxicity, stomatitis and tiredness. Serious but uncommon risks include interstitial lung disease, QT prolongation and cardiomyopathy; patients should report new cough, breathlessness or palpitations and undergo routine monitoring.
Storage
Store Osiem below 30°C in a dry place, in the original bottle, out of children's reach. Use before the expiry date.
Why Choose the GLT?
GLT verifies each Osiem batch against the manufacturer's documentation and provides a transparent, traceable supply route for Lao generics. Lao-made osimertinib is typically several times cheaper than the branded originator in Western markets, which makes long-term EGFR-targeted treatment far more affordable. We provide clear purchase documentation and direct, responsive support for both patients and institutions.
How to Order Osiem from GLT
Message GLT on WhatsApp at +86 15234153837 or email [email protected] to order Osiem 80 mg (30 tablets). Tell us your quantity, destination and order type, and we will confirm availability, batch details and shipping terms before dispatch.
FAQ
What does TLPH stand for? TLPH stands for Trans Continental Life Science & Pharmaceuticals, the Lao manufacturer of Osiem.
Is Osiem the same as Tagrisso? Osiem contains the same active ingredient (osimertinib) and dose as Tagrisso, manufactured in Laos by TLPH.
Where can I order Osiem? GLT can supply Osiem internationally; contact us on WhatsApp or email for availability.