Regorafenib (Stivarga) 40mg*28's | Bayer China-Sourced | GLT

Generic Information: Stivarga (China)

Stivarga is Bayer's originator brand of regorafenib, and this is the China-market presentation supplied by Bayer AG. Each pack contains 28 film-coated tablets of 40 mg. In China, Stivarga is approved and has been included in the national medical insurance drug list, which has significantly improved patient access to this later-line therapy for colorectal cancer, gastrointestinal stromal tumour and hepatocellular carcinoma.

What Is Stivarga Used For?

This China-sourced Stivarga is used for the same three indications as in the rest of the world. It treats metastatic colorectal cancer that has progressed after standard chemotherapy and targeted therapy, gastrointestinal stromal tumour resistant to imatinib and sunitinib, and hepatocellular carcinoma that has progressed on sorafenib. It is a later-line option used to slow progression and extend survival when earlier treatments stop working.

How Does Regorafenib (Stivarga) Work?

Regorafenib is a multi-kinase inhibitor that blocks VEGF receptors 1, 2 and 3, TIE2, PDGFR-α and β, FGFR-1 and 2, KIT, RET, RAF-1 and BRAF. Because it hits both the signals that drive tumour-cell growth and the pathways that build new blood vessels, it suppresses tumour progression across several different cancer types, which is why one molecule can serve colorectal, stromal-tumour and liver-cancer patients alike.

Indications

The approved indications are advanced colorectal cancer after prior chemotherapy, imatinib- and sunitinib-resistant gastrointestinal stromal tumour, and sorafenib-refractory hepatocellular carcinoma. In China, Stivarga is prescribed by oncology specialists, and patients must have adequate liver function and controlled blood pressure before starting treatment.

Dosage

The recommended dose is 160 mg (four 40 mg tablets) once daily with a low-fat meal, in 28-day cycles of 21 days on and 7 days off. A 28-tablet pack covers one week of active dosing. The dose is often reduced to 120 mg or 80 mg daily if hand-foot skin reaction, diarrhoea or liver enzyme elevation occurs, then titrated back up when tolerated.

Side Effects

The most common side effects are hand-foot skin reaction, diarrhoea, fatigue, reduced appetite, hypertension and mouth inflammation. Important but less frequent events include liver injury, bleeding, gastrointestinal perforation and heart problems. Liver function tests, blood pressure and blood counts should be checked regularly, and patients should report skin changes, persistent diarrhoea, black stools or chest pain without delay.

Storage

Keep Stivarga tablets at room temperature in the original packaging, protected from moisture, and out of the reach of children. Do not use after the expiry date printed on the pack.

Why Choose Stivarga Through GLT?

GLT can supply genuine China-market Stivarga for patients and institutions that prefer the Bayer originator product. Sourcing from the China market can offer a meaningful cost advantage over Western list prices while retaining full originator quality, and we ship worldwide from a Hong Kong-licensed facility.

How to Order

To order Stivarga (regorafenib) from GLT, contact us on WhatsApp at +86 15234153837 or by email at [email protected]. We will confirm current availability, pricing and delivery to your country, and we ship from a Hong Kong-licensed facility.

FAQ

Is the China-market Stivarga the same product as elsewhere? Yes — it is the same Bayer originator regorafenib, packaged for the China market.

How long does a 28-tablet pack last? At the standard 160 mg daily dose, seven days of the 21-day active phase.

Do I need a prescription? Yes, a valid prescription from a licensed oncologist is required.