Lumakras (Sotorasib) 120mg Tablets | KRAS G12C NSCLC & mCRC | Amgen Boao China | GLT
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Generic Information: Lumakras (Sotorasib) — China (Boao, Hainan)
Lumakras (sotorasib) is Amgen's first-in-class KRAS G12C inhibitor. For patients in mainland China, the therapy first became reachable through the Boao (Hainan) medical pilot zone — a special policy area that lets approved international medicines be used before nationwide NMPA registration is complete. The China-sourced Lumakras is the same Amgen originator product, manufactured to global GMP standards and aligned with China's regulatory requirements, giving eligible patients early access to a drug that had no local equivalent.
What Is Lumakras (Sotorasib) Used For?
Lumakras is prescribed for adults whose cancer carries the KRAS G12C mutation:
- KRAS G12C-mutated non-small cell lung cancer (NSCLC) that is locally advanced or metastatic, after at least one prior systemic therapy.
- KRAS G12C-mutated metastatic colorectal cancer (mCRC).
How Does Lumakras (Sotorasib) Work?
The KRAS G12C mutation keeps the KRAS signalling protein stuck in its growth-promoting "on" state. Sotorasib forms an irreversible bond with the mutant's cysteine residue, holding KRAS in the inactive state so the runaway growth signal is silenced. Because the drug homes in on the mutant protein specifically, normal cells are comparatively untouched, which is what makes the treatment tolerable as a daily oral tablet.
Indications
- KRAS G12C-mutated locally advanced or metastatic NSCLC after prior systemic therapy
- KRAS G12C-mutated metastatic colorectal cancer
Dosage & Administration
The recommended dose is 960 mg once daily, taken as eight 120 mg tablets with or without food. The China-sourced Lumakras is supplied as 120 mg tablets in a 120-count pack. Swallow the tablets whole and continue until progression or unacceptable toxicity, following your oncologist's guidance on any dose changes.
Side Effects
Common reactions include diarrhoea, nausea, vomiting, fatigue, musculoskeletal pain, reduced appetite, cough and raised liver enzymes (ALT/AST). The important risks are hepatotoxicity, interstitial lung disease or pneumonitis, and QT prolongation, so liver function and any new lung symptoms are monitored during treatment.
Storage & Handling
Store Lumakras tablets at room temperature (20–25 °C) in the original container, protected from moisture and light, and out of reach of children.
Why Choose Lumakras (Sotorasib) from China?
- Early mainland access — sourced from Amgen's Boao (Hainan) pilot zone, the first route to this therapy in China.
- Same Amgen originator product — manufactured under global GMP standards and aligned with NMPA requirements.
- Oral, once-daily targeted therapy — no infusion visits required.
- GLT sourcing — GIVE LIFE TIME LIMITED ships batch-traceable China-sourced Lumakras with full documentation.
How to Order Lumakras (Sotorasib) from GLT?
- Contact GLT via WhatsApp +86 15234153837 or email [email protected] with the quantity you need.
- Receive a formal quotation, payment instructions and delivery estimate.
- Complete payment through our secure channel (Hao Yi Lian / 好易联).
- Your order is dispatched with batch documentation and tracking to delivery.
GLT serves licensed institutions and individual patients; a valid prescription may be requested before dispatch.
FAQ
1. Is Lumakras (sotorasib) available in China?
Yes — the China-sourced Lumakras is supplied from Amgen's Boao (Hainan) medical pilot zone, the first access point for this therapy in mainland China. Contact GLT for availability.
2. What is the price of sotorasib in China?
Contact GLT for a formal quotation based on your quantity and destination. Batch-traceable originator supply is provided with documentation.
3. How is Lumakras different from generic sotorasib?
Lumakras is the original Amgen product; generics are made by other companies with the same active ingredient. GLT supplies both.
4. Where can I buy sotorasib?
You can buy Lumakras and generic sotorasib through GLT via WhatsApp +86 15234153837 or email [email protected].
5. Does sotorasib require a prescription?
Yes, sotorasib is a prescription medicine, and a valid prescription may be requested before dispatch.