Mekinist (Trametinib) 2mg Tablets | MEK Inhibitor | Novartis Hong Kong | GLT

This product is Mekinist, the Novartis originator trametinib, supplied from the Hong Kong, China market. The Hong Kong presentation carries bilingual English and Chinese labeling in line with local Department of Health requirements. It is the same originator medicine registered in many other jurisdictions for BRAF-mutant cancers.

Generic Information: Mekinist (Trametinib)

Each tablet contains 2 mg of trametinib, a selective inhibitor of MEK1 and MEK2. Trametinib works in the MAPK signaling pathway, the same pathway that dabrafenib targets one step earlier. The two drugs are frequently prescribed together as a combined BRAF/MEK regimen.

What Is Mekinist (Trametinib) Used For?

Mekinist is indicated for cancers driven by a BRAF V600 mutation: unresectable or metastatic melanoma, adjuvant melanoma after surgery (with dabrafenib), and BRAF V600E-mutated metastatic non-small cell lung cancer and anaplastic thyroid cancer, both in combination with dabrafenib.

How Does Mekinist Work?

Trametinib is a reversible, allosteric inhibitor of MEK1 and MEK2. It shuts down the overactive MAPK signal that BRAF-mutant tumor cells rely on, slowing their growth and promoting cell death. Pairing it with dabrafenib blocks two points of the same pathway for a stronger, more durable effect.

Indications

• BRAF V600E/K-mutant unresectable or metastatic melanoma
• Adjuvant melanoma with dabrafenib
• BRAF V600E metastatic NSCLC with dabrafenib
• BRAF V600E anaplastic thyroid cancer with dabrafenib

Dosage & Administration

The recommended dose is 2 mg once daily, with or without food, at the same time each day. Swallow the tablet whole. Dosing is adjusted by the oncologist as needed for tolerability.

Side Effects

Rash, diarrhea, fatigue, nausea, limb swelling and fever are common. Serious risks include heart failure, blood clots, severe skin toxicity, retinal vein occlusion, interstitial lung disease and bleeding. Heart, skin and eye monitoring are standard during treatment.

Storage & Handling

Keep at room temperature in the original container, away from moisture and light, and out of children's reach. Do not use after expiry.

Why Choose the GLT?

• Hong Kong-sourced originator — Mekinist with bilingual labeling.
• Authentic Novartis product — with batch documentation.
• Reliable delivery — worldwide shipping with tracking.

How to Order Mekinist (Hong Kong) from GLT

1. Contact GLT via WhatsApp +86 15234153837 or email [email protected].
2. Receive a quotation and delivery estimate.
3. Pay via Hao Yi Lian / 好易联.
4. Shipment dispatches with documentation and tracking.

A valid prescription may be requested before dispatch. Institutions and individual patients are both served.

FAQ

1. Where is this Mekinist sourced from?

This Mekinist is sourced from the Hong Kong, China market.

2. What strength is available?

This listing is for 2 mg tablets.

3. Do I need a prescription?

Yes, trametinib is prescription-only.