Bosentas (Bosentan) 62.5mg/125mg*30's | Generic Endothelin Receptor Antagonist | GLT
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Generic Information: Bosentas (India)
Bosentas is an Indian generic of bosentan, manufactured by Cipla Ltd., one of the world's leading generic pharmaceutical companies. It is supplied in 62.5 mg and 125 mg strengths, each in a 30-tablet pack, covering both the starting and maintenance doses of the standard bosentan regimen. As a generic dual endothelin receptor antagonist, Bosentas delivers the same active ingredient as the originator at a much lower, out-of-pocket-friendly price.
What Is Bosentas Used For?
Bosentas is used to treat pulmonary arterial hypertension (PAH), WHO functional class II to IV, improving exercise ability and reducing clinical worsening. It is an oral, twice-daily medicine that is practical for long-term home use, and it is prescribed after a specialist confirms the diagnosis of PAH. The medicine is suitable for patients with idiopathic PAH, PAH associated with connective tissue disease, or PAH associated with congenital heart disease.
How Does Bosentas (Bosentan) Work?
The bosentan in Bosentas is a dual endothelin receptor antagonist that blocks both the ETA and ETB receptors. By counteracting endothelin-1, a potent vasoconstrictor that is elevated in PAH, it relaxes the lung's blood vessels, lowers pulmonary vascular resistance, and eases the load on the right side of the heart. The generic delivers the same pharmacology as the originator, which is why it can be used as a cost-saving substitute.
Indications
Bosentas is indicated for adults with pulmonary arterial hypertension (WHO Group 1), functional class II to IV. It slows disease progression and improves symptoms when taken as long-term therapy. The medicine is not a cure, and it requires regular liver and blood-count monitoring during treatment.
Dosage
The standard regimen starts at 62.5 mg twice daily for four weeks, then increases to 125 mg twice daily. The 62.5 mg and 125 mg strengths in this listing cover both phases. Take the tablets morning and evening, with or without food. Liver enzymes are checked before starting and monthly, and women of childbearing potential must use reliable contraception.
Side Effects
Common side effects include headache, flushing, fluid retention, and abnormal liver function tests. A dose-related drop in hemoglobin can occur, so blood counts are monitored. The serious risks are liver toxicity and birth defects, which is why monthly liver monitoring and strict contraception are essential during treatment.
Storage
Store Bosentas below 30°C in a dry place, in its original packaging, and away from children. No refrigeration is needed.
Why Choose the GLT?
For patients paying out of pocket, a generic such as Bosentas from India offers a major price advantage over the originator brand. The originator's Western list price is very high, while Indian generic bosentan is priced far more affordably, which can make years of daily therapy financially sustainable. GLT sources from established manufacturers and helps buyers obtain the documentation needed for safe import.
How to Order
To order Bosentas through GLT, contact us on WhatsApp at +86 15234153837 or email [email protected]. Let us know the strength, quantity, and your destination, and we will confirm availability, sourcing, and shipping terms for your region.
FAQ
Is Bosentas a generic of Tracleer? Yes. Bosentas is an Indian generic of bosentan, the active ingredient in Tracleer, produced by Cipla.
What strengths does Bosentas come in? Bosentas is available in 62.5 mg and 125 mg tablets, each in a 30-tablet pack, covering both the starting and maintenance doses.
Can I buy generic bosentan online? Many patients source generic bosentan through international suppliers like GLT. Always confirm the supplier is legitimate and provides proper documentation before ordering.