KeZeRui 科瑞泽 (Avatrombopag) 20mg*10 Tablets | Sichuan Kelun China | GLT

Generic Information: KeZeRui (Avatrombopag) — Sichuan Kelun, China

KeZeRui (科瑞泽) is Sichuan Kelun Pharmaceutical Co., Ltd.'s avatrombopag maleate tablet — the product of China's largest infusion and one of its most vertically integrated manufacturers, listed in both Shenzhen and Hong Kong. Approved in November 2024 under 国药准字H20249300, the brand joined the national volume-based procurement program in its latest round and won a supplier slot, which mechanically made it one of the lowest-cost genuine avatrombopag channels in the world. The pack here is ten 20 mg film-coated tablets, matching the originator presentation.

What Is KeZeRui Used For?

Its registration serves adults with chronic liver disease related thrombocytopenia ahead of elective procedures, with the ITP population covered through the class pathway as filings mature. For buyers abroad, the procurement angle is the story: when a Chinese national tender selects a generic, hospital channels dispense it at a fraction of originator pricing — and GLT's quotation for KeZeRui reflects exactly that structural discount rather than arbitrary markdown. Chronic liver disease patients should still read the label boundary: this is a pre-procedure bridge, not daily count maintenance.

How Does KeZeRui Work?

Avatrombopag stimulates the thrombopoietin receptor (c-Mpl) at the transmembrane domain on megakaryocyte progenitor cells — second-generation pharmacology that adds to, rather than competes with, natural thrombopoietin signaling. Megakaryocytes respond by maturing and releasing platelets within three to five days of the first tablet. Kelun's API-plus-formulation integration backs the tablet: the company synthesized its own active ingredient, cleared it with the regulator, and feeds its own finished-dose lines — supply-chain depth that matters when hospital demand spikes after procurement wins.

Indications of KeZeRui (China Label)

The approved insert reads: thrombocytopenia in adult patients with chronic liver disease scheduled to undergo elective diagnostic procedures or surgery. Kelun's procurement listing applies to this indication under China's reimbursement rules, which ties hospital dispensing to the CLD procedure population. Broader uses — chronic ITP maintenance, antiviral-associated counts — sit outside the current insert and belong to specialist discretion where practiced.

Dosage and Administration

One daily dose with food, tablets swallowed whole. The CLD course runs: start ten to thirteen days before the procedure; take 60 mg (three tablets) daily for five days if platelets are below 40×10⁹/L, or 40 mg (two tablets) daily for five days at 40 to below 50×10⁹/L; perform the procedure five to eight days after the final tablet, with a count check that day to confirm readiness. Missed dose: take when remembered with food; never double the next day.

Side Effects of KeZeRui

The class profile applies: fever, headache, abdominal pain, nausea, fatigue and peripheral edema are the commonly reported effects in liver-disease patients. The labeled serious concern is thromboembolism as counts rise — hence scheduled platelet checks and automatic dose steps at overshoot. Any sudden breathlessness, chest pain, severe headache or unilateral limb swelling demands immediate care. Hypersensitivity to any component excludes use.

Storage Instructions

Keep tablets in the original blister inside the carton, stored dry, below 25°C, away from strong light. Refrigeration is unnecessary. Store out of children's reach and return unused stock to a pharmacy at course end.

Why Choose KeZeRui from GLT?

KeZeRui is the answer to one specific question — where does genuine avatrombopag cost least without leaving the regulated supply chain? A national procurement winner from a top-tier integrated manufacturer is the structural answer, and GLT passes that economics through with sealed packaging, batch photographs, and quotations set beside the China original and the Lao/Bangladesh alternatives so buyers see the real spread. Contact is direct: WhatsApp +86 15234153837 or [email protected], answered by the GLT team that ships the boxes.

How to Order KeZeRui (Avatrombopag)

Send quantity and destination to WhatsApp +86 15234153837 or [email protected]. GLT replies with a formal quotation — courier choices, payment routes, lead time — usually inside one working day, and dispatches sealed stock with export documentation on confirmation. Repeat orders and institutional volumes can be placed on schedule with documentation support.

FAQ

What does the Chinese name 科瑞泽 mean for me? It is Kelun's registered brand name for avatrombopag — boxes marked KeZeRui/科瑞泽 with H20249300 are the genuine article.

Why is this version so much cheaper? It won a slot in China's national volume-based procurement, where guaranteed hospital volume trades for steep price reduction — the discount is structural, not a quality compromise.

Is Kelun a reliable manufacturer? It is among China's largest pharmaceutical companies by revenue, listed in Shenzhen and Hong Kong, with its own API production feeding the finished tablets — among the most audited supply chains in the domestic industry.

Does procurement pricing change the medicine? No — the tablet evaluated for consistency is the tablet dispensed; only the channel price differs.

Can I mix KeZeRui with the imported original across months? Medically the molecule is the same, but brand switching should be flagged to the treating physician so monitoring stays coherent.