Cotelni (Trametinib) 2mg*30's | Generic MEK Inhibitor | Cipla Ltd. | GLT
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Cotelni is Cipla's generic trametinib, manufactured in India. Cipla is one of the world's largest pharmaceutical companies and a major supplier of affordable oncology medicines; its 2 mg trametinib tablet brings BRAF/MEK targeted therapy within reach of many more patients.
Generic Information: Cotelni (Trametinib)
Cipla Ltd. is a globally recognized Indian pharmaceutical manufacturer with an extensive oncology portfolio and long-standing export footprint. Cotelni is its trametinib brand, containing the same 2 mg active ingredient as the originator Mekinist and produced under GMP standards.
What Is Cotelni (Trametinib) Used For?
Cotelni is indicated for BRAF V600-mutated cancers: unresectable or metastatic melanoma, adjuvant melanoma with dabrafenib, and BRAF V600E-mutated metastatic non-small cell lung cancer and anaplastic thyroid cancer with dabrafenib.
How Does Cotelni Work?
The trametinib in Cotelni inhibits MEK1 and MEK2, cutting the MAPK pathway signal that BRAF-mutant tumors rely on. This slows tumor growth and can induce cancer-cell death. It is typically used with dabrafenib for dual pathway blockade.
Indications
- BRAF V600-mutant unresectable or metastatic melanoma
- Adjuvant melanoma with dabrafenib
- BRAF V600E metastatic NSCLC with dabrafenib
- BRAF V600E anaplastic thyroid cancer with dabrafenib
Dosage & Administration
The standard dose is 2 mg once daily, with or without food, swallowed whole. Dose adjustments are made by the oncologist.
Side Effects
Rash, diarrhea, fatigue, nausea, swelling and fever are common. Serious risks include cardiomyopathy, blood clots, severe skin reactions, eye problems, lung inflammation and bleeding. Regular monitoring is part of treatment.
Storage & Handling
Store at room temperature in the original package, away from moisture and light, out of children's reach, and not past expiry.
Why Choose Cotelni?
- Cipla generic — from a leading global pharmaceutical manufacturer.
- 2 mg standard strength — matches the originator dosing.
- Affordable — lower-cost trametinib for BRAF/MEK therapy.
How to Order Cotelni from GLT
- Contact GLT via WhatsApp +86 15234153837 or email [email protected].
- Receive a quotation and delivery estimate.
- Pay via Hao Yi Lian / 好易联.
- Dispatch with documentation and tracking.
A valid prescription may be requested before dispatch. Institutions and individual patients are served.
FAQ
1. Who manufactures Cotelni?
Cotelni is manufactured by Cipla Ltd. in India.
2. Is Cotelni a generic of Mekinist?
Yes, it is a generic trametinib with the same 2 mg active ingredient.
3. Do I need a prescription?
Yes, trametinib is prescription-only.