MEQSEL (Trametinib) 0.5mg*30's | Generic MEK Inhibitor | Novartis India | GLT

MEQSEL is Novartis's lower-strength presentation of trametinib, supplied from India in 0.5 mg tablets. This half-milligram strength is used for dose reduction and for pediatric dosing in BRAF-mutated low-grade glioma, where body-weight-based dosing requires finer increments than the standard 2 mg tablet allows.

Generic Information: MEQSEL (Trametinib)

Trametinib is a MEK1/MEK2 inhibitor used in BRAF/MEK targeted therapy. The 0.5 mg tablet in this listing is the low-dose option in the trametinib range, complementing the standard 2 mg strength. It is manufactured by Novartis India and is the same molecule as the originator Mekinist.

What Is MEQSEL (Trametinib) Used For?

MEQSEL is used for BRAF V600-mutated cancers, including unresectable or metastatic melanoma, adjuvant melanoma with dabrafenib, and BRAF V600E-mutated metastatic non-small cell lung cancer and anaplastic thyroid cancer. Its 0.5 mg strength is especially relevant where a reduced or weight-based dose is indicated.

How Does MEQSEL Work?

The trametinib in MEQSEL blocks MEK1 and MEK2, cutting the MAPK pathway signal that BRAF-mutant tumors depend on. This suppresses tumor growth and can induce cancer-cell death. It is typically used with a BRAF inhibitor such as dabrafenib for a two-point blockade.

Indications

• BRAF V600-mutant unresectable or metastatic melanoma
• Adjuvant melanoma therapy with dabrafenib
• BRAF V600E metastatic NSCLC with dabrafenib
• BRAF V600E anaplastic thyroid cancer with dabrafenib

Dosage & Administration

The usual adult dose is 2 mg once daily; the 0.5 mg tablet is used when a lower dose is required, such as for dose reduction or weight-based pediatric dosing. Tablets are swallowed whole. Any dose adjustment is directed by the treating physician.

Side Effects

Rash, diarrhea, fatigue, nausea, peripheral edema and fever are common. Serious risks include cardiomyopathy, thromboembolism, severe skin reactions, ocular toxicity, interstitial lung disease and hemorrhage. Monitoring of heart function and of skin and eyes is required.

Storage & Handling

Store at room temperature in the original packaging, protected from moisture and light, out of children's reach, and not past expiry.

Why Choose MEQSEL?

• Low-dose 0.5 mg strength — for dose reduction and weight-based dosing.
• Novartis-manufactured — the originator molecule in a lower strength.
• Flexible regimen — finer dose increments than the 2 mg tablet.

How to Order MEQSEL from GLT

1. Contact GLT via WhatsApp +86 15234153837 or email [email protected].
2. Receive a quotation and delivery estimate.
3. Pay through Hao Yi Lian / 好易联.
4. Goods ship with documentation and tracking.

A valid prescription may be requested before dispatch. Institutions and individual patients are served.

FAQ

1. Is MEQSEL the same as Mekinist?

Yes, MEQSEL contains the same trametinib active ingredient, supplied as a lower 0.5 mg strength.

2. Who manufactures MEQSEL?

MEQSEL is manufactured by Novartis India.

3. Do I need a prescription?

Yes, trametinib is prescription-only.