Avalet-20 (Avatrombopag) 20mg*28 Tablets | Drug International Bangladesh | GLT
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Generic Information: Avalet-20 (Avatrombopag) — Drug International Ltd., Bangladesh
Avalet-20 is the avatrombopag film-coated tablet of Drug International Ltd. (DIL), one of Bangladesh's longer-established manufacturers, produced at the company's Unit-3 plant in Tongi, Gazipur under manufacturing licenses 315 and 523. Each silver carton holds 28 tablets at 20 mg — the full month's supply an ITP maintenance patient needs at the standard starting dose, or the convenient one-box format for anyone comparing versions. Bangladesh's regulatory authority registers the product for local use and export, and DIL stamps every carton with its QR-traceable label that buyers can check on arrival.
What Is Avalet-20 Used For?
The registered indications follow the originator's: low platelet counts in adults with chronic liver disease who are scheduled to undergo a medical or dental procedure, and chronic immune thrombocytopenia in adults inadequately controlled by previous therapy. Practically, the 28-tablet pack maps neatly onto both journeys — a single box covers an ITP month at 20 mg daily, while for the five-day pre-procedure course one box leaves plenty of reserve if the physician extends monitoring or a second procedure window appears.
How Does Avalet-20 Work?
The tablet delivers avatrombopag maleate, equivalent to 20 mg of avatrombopag base per film-coated tablet. The molecule activates the thrombopoietin receptor (c-Mpl) on megakaryocyte progenitor cells from the transmembrane domain, amplifying the same intracellular pathway natural thrombopoietin uses — additive, not competitive. Platelet production rises within days, and since the compound neither chelates divalent cations nor depends on an empty stomach, it can be taken with any ordinary meal, a meaningful convenience for cirrhotic patients who already manage complex medication schedules.
Indications of Avalet-20 (Bangladesh)
Bangladesh's label mirrors the FDA framework: thrombocytopenia in chronic liver disease ahead of procedures, and chronic ITP after insufficient response to prior treatment. Local hematologists also apply it in the supportive-care scenarios the class is used for, always off-protocol and by specialist decision. Buyers should note what it is not registered for: dengue-associated thrombocytopenia has no approval anywhere for this class, and responsible suppliers decline those requests.
Dosage and Administration
One tablet daily with food, swallowed whole. Before a procedure in chronic liver disease: ten to thirteen days out, begin a five-day course — 60 mg (three tablets) daily if the starting count is below 40×10⁹/L, or 40 mg (two tablets) daily if it sits between 40 and just under 50×10⁹/L — with the procedure five to eight days after the last dose. For chronic ITP: start at 20 mg daily and let the physician titrate up to a maximum of 40 mg daily to hold counts at or above 50×10⁹/L, checking blood weekly until stable. Miss one dose? Take it when remembered with food; never double up.
Side Effects of Avalet-20
Fever, headache, stomach ache, nausea, tiredness and swollen ankles are the frequent complaints among liver-disease patients; ITP users report headache, fatigue, bruising, nosebleeds, gum bleeding, joint pain and throat infections more often. The boxed concern of the class applies — arterial and venous clots — so counts are monitored and overshoots handled by dose reduction. Any unexplained severe headache, vision change, chest pain or limb swelling warrants same-day medical review.
Storage Instructions
Store below 30°C in a dry place inside the original carton, away from light. No refrigeration. Keep the bottle or blister sealed until use and out of children's reach; discard expired stock through a pharmacy take-back.
Why Choose Avalet-20 from GLT?
Avalet-20 is the value play of the Bangladesh line: a 28-tablet box from a manufacturer with decades of export history, packed in a format that suits ongoing ITP therapy rather than just the five-day bridge. GLT sources directly, verifies every lot with pre-shipment photographs of the exact cartons to be shipped, and lays out the whole family for comparison — the China original, five domestic Chinese generics, this DIL pack and its Bangladeshi and Lao rivals — so the decision is made on documented facts. Questions go to a person, not a ticket queue: WhatsApp +86 15234153837 or [email protected].
How to Order Avalet-20 (Avatrombopag)
Send quantity and country to WhatsApp +86 15234153837 or email [email protected]. GLT returns a formal quotation with courier and payment options, usually within a working day, and ships sealed cartons with full export documents on confirmation. Multi-box schedules for continuous therapy can be arranged with reminders before each refill.
FAQ
Who is Drug International Ltd.? A Bangladeshi manufacturer founded decades ago in Dhaka, operating multiple GMP-certified production units — Unit-3 in Tongi, Gazipur makes Avalet under licenses 315 and 523.
Why 28 tablets per box? It matches one month of once-daily ITP dosing — the pack design follows how chronic patients actually consume the medicine.
How does Avalet compare with the Chinese or Lao versions? Same 20 mg molecule; differences are maker, pack size, price and logistics. GLT quotes all of them side by side so you choose with numbers in front of you.
Can Avalet be used for dengue-related low platelets? No — no TPO receptor agonist is approved for dengue thrombocytopenia; using it that way is off-label risk without evidence.
What proofs of authenticity come with the shipment? Pre-shipment photographs of the exact cartons, batch and expiry details, and complete export paperwork that lets your pharmacist verify the pack against DIL's published design.