Mekinist (Trametinib) 2mg Tablets | MEK Inhibitor | Novartis India | GLT

This listing supplies Mekinist, the Novartis originator trametinib, from the Indian market in 2 mg tablets. India is one of Novartis's key emerging markets for oncology, and Mekinist distributed there carries the same active ingredient and dosage as the product sold in the United States and Europe, adapted to Indian packaging and distribution.

Generic Information: Mekinist (Trametinib)

Trametinib is an oral inhibitor of the MEK1 and MEK2 kinases. These enzymes relay the growth signal from mutated BRAF in cancers such as melanoma, and blocking them is the basis of modern BRAF/MEK targeted therapy. Mekinist is the originator form of trametinib, developed by Novartis.

What Is Mekinist (Trametinib) Used For?

The medicine treats BRAF V600-mutated cancers. It is approved for unresectable or metastatic melanoma, for adjuvant treatment of melanoma together with dabrafenib after surgery, and for BRAF V600E-mutated metastatic non-small cell lung cancer and anaplastic thyroid cancer, also with dabrafenib.

How Does Mekinist Work?

By binding MEK1 and MEK2, trametinib stops the MAPK pathway signal that BRAF-mutant tumor cells depend on. The result is reduced tumor growth and, in many patients, tumor shrinkage. Combining trametinib with dabrafenib attacks the pathway at two levels and is standard care for most BRAF-mutant advanced cancers.

Indications

• Unresectable or metastatic BRAF V600-mutant melanoma
• Adjuvant melanoma therapy with dabrafenib
• Metastatic BRAF V600E NSCLC with dabrafenib
• Anaplastic thyroid cancer with dabrafenib

Dosage & Administration

Take one 2 mg tablet once daily at the same time each day, with or without food. Swallow whole with water. The dose may be lowered or paused by the oncologist in response to side effects.

Side Effects

Common reactions include rash, diarrhea, fatigue, nausea, peripheral swelling and fever. Serious risks include cardiomyopathy, blood clots, severe skin reactions, retinal vein occlusion, interstitial lung disease and bleeding. Regular monitoring of heart function and of skin and eye symptoms is required.

Storage & Handling

Store at room temperature in the original packaging, protected from moisture and light, out of children's reach, and not past expiry.

Why Choose the GLT?

• India-sourced originator — genuine Novartis Mekinist.
• Once-daily dosing — simple oral regimen.
• Global logistics — GLT handles documentation and delivery.

How to Order Mekinist (India) from GLT

1. Reach GLT at WhatsApp +86 15234153837 or email [email protected] with the quantity required.
2. Receive a quotation and delivery schedule.
3. Complete payment via Hao Yi Lian / 好易联.
4. Dispatch with documentation and tracking.

A valid prescription may be requested before dispatch. Institutions and individual patients are served.

FAQ

1. Is this Mekinist the same as the US or EU product?

Yes, it contains the same trametinib active ingredient and dosing; it is the originator supplied from India.

2. What is the strength?

This listing is for 2 mg tablets.

3. Is a prescription required?

Yes, trametinib is prescription-only.